Description

(S)-1-n-Cbz-2-Methyl-Piperazine is a high-purity chiral piperazine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology industries focused on drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• API Development: Used in constructing the core scaffold of potential Active Pharmaceutical Ingredients (APIs) requiring specific (S)-configuration.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Peptidomimetics: Integral for designing and synthesizing peptide-like molecules with enhanced metabolic stability and bioavailability.
• Medicinal Chemistry Research: A valuable tool compound for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Serves as a starting material for the contract manufacturing of specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	(S)-1-n-Cbz-2-Methyl-Piperazine
CAS No.	923565-98-4
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	(S)-1-(Benzyloxycarbonyl)-2-methylpiperazine; (S)-1-Cbz-2-Methylpiperazine; (S)-2-Methyl-1-(phenylmethoxy)carbonylpiperazine; (S)-N-Carbobenzoxy-2-methylpiperazine; (S)-1-[(Benzyloxy)carbonyl]-2-methylpiperazine; (2S)-1-[(Benzyloxy)carbonyl]-2-methylpiperazine; (S)-1-CBZ-2-METHYLPIPERAZINE; 923565-98-4
EINECS	Contact for details

Quality Control

Our (S)-1-n-Cbz-2-Methyl-Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), chiral purity, and impurity profiles. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.