Description

1H-Purine-2,6-Dione, 3,9-Dihydro-1,3,9-Trimethyl-8-(2-Pyrimidinylthio)- is a specialized purine derivative, a key chemical scaffold in medicinal chemistry and pharmaceutical research. This compound matters as a high-value building block for the synthesis of novel therapeutic agents, particularly those targeting neurological and metabolic pathways. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel purine-based drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Employed in enzymatic assays and as a probe to study purinergic signaling pathways.
• Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.
• Academic Research: Applied in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug development projects.

Basic Information

Product Name	1H-Purine-2,6-Dione, 3,9-Dihydro-1,3,9-Trimethyl-8-(2-Pyrimidinylthio)-
CAS No.	923557-88-4
Molecular Formula	C12H14N6O2S
Molecular Weight	306.35 g/mol
Synonyms	8-[(Pyrimidin-2-yl)thio]-1,3,9-trimethyl-3,9-dihydro-1H-purine-2,6-dione; 1,3,9-Trimethyl-8-(pyrimidin-2-ylthio)xanthine; 8-(2-Pyrimidinylthio)-1,3,9-trimethylxanthine; 8-(Pyrimidin-2-ylsulfanyl)-1,3,9-trimethyl-3,9-dihydro-1H-purine-2,6-dione; 1,3,9-Trimethyl-8-(pyrimidin-2-ylsulfanyl)-1H-purine-2,6(3H,9H)-dione; 8-(2-Pyrimidylthio)-1,3,9-trimethylxanthine; 8-(Pyrimidin-2-ylthio)-1,3,9-trimethyl-3,9-dihydro-1H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our high-purity 1H-Purine-2,6-Dione derivative is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.