Description

1-(3,4-Difluorobenzoyl)Piperazine is a high-value pharmaceutical intermediate and fine chemical building block. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, agrochemical manufacturers, and advanced material scientists for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides containing difluorobenzoyl motifs.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals due to its rigid aromatic and piperazine structure.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	1-(3,4-Difluorobenzoyl)Piperazine
CAS No.	923237-42-7
Molecular Formula	C11H12F2N2O
Molecular Weight	226.22 g/mol
Synonyms	1-(3,4-Difluorobenzoyl)piperazine; 3,4-Difluorophenyl(piperazin-1-yl)methanone; Piperazine, 1-(3,4-difluorobenzoyl)-; 923237-42-7; 1-Piperazinecarboxylic acid, 3,4-difluorobenzoyl-; (3,4-Difluorophenyl)(piperazin-1-yl)methanone; N-(3,4-Difluorobenzoyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(3,4-Difluorobenzoyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.