Description

3-Piperidinecarboxylic Acid, 1-[[(2,4-Difluorophenyl)Amino]Carbonyl]- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key piperidine-carboxamide scaffold for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its piperidine core and amide functionality.
• API Synthesis: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Tool Compound: Potential use in developing enzyme inhibitors or receptor modulators for biochemical assays.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	3-Piperidinecarboxylic Acid, 1-[[(2,4-Difluorophenyl)Amino]Carbonyl]-
CAS No.	923207-45-8
Molecular Formula	C13H14F2N2O3
Molecular Weight	284.26 g/mol
Synonyms	1-[(2,4-Difluorophenyl)carbamoyl]piperidine-3-carboxylic acid; N-(2,4-Difluorophenyl)-3-piperidinecarboxamide-1-carboxylic acid; 3-Piperidinecarboxylic acid, 1-[(2,4-difluorophenyl)aminocarbonyl]-; 923207-45-8; UNII-9K3F8S5F5H; 9K3F8S5F5H; 1-[(2,4-Difluorophenyl)carbamoyl]piperidine-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques including HPLC, GC, NMR, and MS to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are available upon request. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.