Description

4-[Oxo(Piperazin-1-Yl)Acetyl]Morpholine is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining morpholine and piperazine moieties. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, particularly those targeting central nervous system (CNS) disorders.
• API Synthesis: Serves as a core scaffold for constructing complex molecules with potential pharmacological activity in medicinal chemistry research.
• Chemical Research & Development: Used as a versatile reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Employed in the manufacture of specialized, high-value chemicals requiring precise molecular architecture.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	4-[Oxo(Piperazin-1-Yl)Acetyl]Morpholine
CAS No.	923125-02-4
Molecular Formula	C10H17N3O3
Molecular Weight	227.26 g/mol
Synonyms	1-(Morpholin-4-yl)-2-(piperazin-1-yl)ethane-1,2-dione; 2-(Piperazin-1-yl)-1-(morpholin-4-yl)ethan-1-one; 4-[2-Oxo-2-(piperazin-1-yl)acetyl]morpholine; N-(Morpholinocarbonylmethyl)piperazine; 923125-02-4
EINECS	Contact for details

Quality Control

Our 4-[Oxo(Piperazin-1-Yl)Acetyl]Morpholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting full compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.