Description

(R)-3-Methylpiperazin-2-One is a high-purity chiral piperazinone derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, essential for achieving desired biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents and other therapeutic small molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a building block for constructing complex, stereochemically defined heterocyclic compounds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Ligand and Catalyst Development: Potential precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	(R)-3-Methylpiperazin-2-One
CAS No.	922178-61-8
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	(R)-3-Methyl-2-piperazinone; (R)-3-Methylpiperazin-2-one; (3R)-3-Methyl-3,4-dihydro-2(1H)-pyrazinone; (R)-3-Methyl-3,4-dihydro-2(1H)-pyrazinone; (R)-3-Methyl-1,4-diazinan-2-one; (R)-3-Methylpiperazine-2-one; (R)-3-Methyl-2-oxopiperazine
EINECS	Contact for details

Quality Control

Our (R)-3-Methylpiperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.