Description

4-(2-Pyrazinyl)-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and pyrazine heterocyclic structure. This compound is of significant value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value organic molecules for specialized applications.
• Building Block for Heterocyclic Compounds: Utilized to construct more complex molecular architectures containing piperidine and pyrazine rings.

Basic Information

Product Name	4-(2-Pyrazinyl)-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	921613-02-7
Molecular Formula	C14H21N3O2
Molecular Weight	263.34 g/mol
Synonyms	tert-Butyl 4-(pyrazin-2-yl)piperidine-1-carboxylate; 1-Boc-4-(2-pyrazinyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(2-pyrazinyl)piperidine; 4-Pyrazin-2-yl-piperidine-1-carboxylic acid tert-butyl ester; Boc-4-(2-pyrazinyl)piperidine; N-Boc-4-(2-pyrazinyl)piperidine
EINECS	Contact for details

Quality Control

Our 4-(2-Pyrazinyl)-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), impurity profile, and physical characteristics. Our quality commitment supports applications in GMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.