Description

1-(4-Acetylpiperazin-1-Yl)-3-Aminopropan-1-One Hydrochloride is a high-purity, pharmaceutically relevant organic salt with the CAS number 917758-58-8. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in sophisticated organic synthesis. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Serves as a precursor for synthesizing molecular probes to study enzyme function and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects in CDMOs (Contract Development and Manufacturing Organizations).
• Acetylpiperazine Derivative Synthesis: Enables the functionalization and creation of diverse acetylpiperazine-based compound libraries for screening.

Basic Information

Item	Detail
Product Name	1-(4-Acetylpiperazin-1-Yl)-3-Aminopropan-1-One Hydrochloride
CAS No.	917758-58-8
Molecular Formula	C9H18ClN3O2
Molecular Weight	235.71 g/mol
Synonyms	3-Amino-1-(4-acetyl-1-piperazinyl)-1-propanone hydrochloride; 1-(4-Acetylpiperazin-1-yl)-3-aminopropan-1-one HCl; 3-Amino-1-(4-acetylpiperazin-1-yl)propan-1-one hydrochloride; N-(3-Oxo-3-(4-acetylpiperazin-1-yl)propyl)amine hydrochloride; 1-Propanone, 3-amino-1-(4-acetyl-1-piperazinyl)-, hydrochloride; 917758-58-8; 4-Acetyl-1-(3-aminopropanoyl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our production of 1-(4-Acetylpiperazin-1-Yl)-3-Aminopropan-1-One Hydrochloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.