Description

n-[1-(3-Azetidinyl)-4-Piperidinyl]-n-Methyl-Carbamic Acid 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound matters for its critical role as a key building block in the synthesis of novel therapeutic agents, particularly those targeting the central nervous system. Pharmaceutical R&D teams and fine chemical manufacturers need this material to develop and scale up production of innovative drug candidates, ensuring a reliable supply chain for preclinical and clinical studies.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a key starting material for developing robust, scalable synthetic routes for new chemical entities (NCEs).
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional labs for studying novel heterocyclic chemistry and pharmacological mechanisms.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	n-[1-(3-Azetidinyl)-4-Piperidinyl]-n-Methyl-Carbamic Acid 1,1-Dimethylethyl Ester
CAS No.	917610-03-8
Molecular Formula	C15H29N3O2
Molecular Weight	283.41 g/mol
Synonyms	tert-Butyl N-methyl-N-[1-(3-azetidinyl)-4-piperidinyl]carbamate; 1,1-Dimethylethyl N-methyl-N-[1-(3-azetidinyl)-4-piperidinyl]carbamate; N-Methyl-N-[1-(azetidin-3-yl)piperidin-4-yl]carbamic acid tert-butyl ester; BOC-protected 3-(4-(N-methylcarbamoyl)piperidin-1-yl)azetidine; AZD-5213 Intermediate; 917610-03-8; N-Methyl-N-(1-(3-azetidinyl)-4-piperidinyl)carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our n-[1-(3-Azetidinyl)-4-Piperidinyl]-n-Methyl-Carbamic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.