Description

4-(3-Amino-Propyl)-Piperazin-2-One is a high-purity, functionalized piperazinone derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a primary amine and a lactam ring, makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning physicochemical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, including kinase inhibitors, receptor modulators, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators requiring specific heterocyclic scaffolds.
• Ligand and Chelator Development: The amine and carbonyl groups provide sites for metal coordination, useful in creating catalysts or imaging agents.
• Polymer Modification: Acts as a monomer or cross-linking agent for producing specialty polymers with enhanced thermal stability or specific functional groups.
• Bioconjugation Chemistry: The primary amine group is readily available for conjugation reactions with biomolecules for diagnostic or therapeutic applications.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-(3-Amino-Propyl)-Piperazin-2-One
CAS No.	917562-07-3
Molecular Formula	C7H15N3O
Molecular Weight	157.22 g/mol
Synonyms	1-(3-Aminopropyl)piperazin-2-one; 3-Aminopropyl-piperazin-2-one; 4-(3-Aminopropyl)-2-piperazinone; 1-(3-Aminopropyl)-2-piperazinone; 2-Piperazinone, 4-(3-aminopropyl)-; 4-(3-Aminopropyl)piperazin-2-one; 4-(3-Amino-propyl)-2-piperazinone; 4-(3-Aminopropyl)-2-piperazinone
EINECS	Contact for details

Quality Control

Our 4-(3-Amino-Propyl)-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.