Description

2-Boc-Amino-1-(4-Carbamoyl-Piperazin-1-Yl)-Ethanone is a high-purity, protected amino acid derivative and a key synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile building block in the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide mimetics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Peptidomimetic Synthesis: Used to introduce protected amino and carbamoyl functionalities into peptide-like structures to enhance stability and bioavailability.
• Chemical Biology Research: Employed in the development of molecular probes and tool compounds for studying enzyme function and protein-protein interactions.
• Process Chemistry Development: Serves as a key starting material for scaling up the production of complex organic molecules under Good Manufacturing Practice (GMP) conditions.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring specialized piperazine derivatives.

Basic Information

Product Name	2-Boc-Amino-1-(4-Carbamoyl-Piperazin-1-Yl)-Ethanone
CAS No.	917202-00-7
Molecular Formula	C₁₂H₂₂N₄O₄
Molecular Weight	286.33 g/mol
Synonyms	1-(4-Carbamoylpiperazin-1-yl)-2-[(tert-butoxycarbonyl)amino]ethanone; 2-[(tert-Butoxycarbonyl)amino]-1-(4-carbamoylpiperazin-1-yl)ethanone; 2-Boc-amino-1-(4-carbamoylpiperazin-1-yl)ethanone; N-Boc-glycine-4-carbamoylpiperazine; Boc-Glycine-4-carbamoylpiperazine; tert-Butyl (2-oxo-2-(4-carbamoylpiperazin-1-yl)ethyl)carbamate; 917202-00-7
EINECS	Contact for details

Quality Control

Our 2-Boc-Amino-1-(4-Carbamoyl-Piperazin-1-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with high-purity research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.