Description

2-Bromo-4-Formylpiperidine CAS NO 916791-91-8 is a versatile and highly functionalized piperidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both a bromo and a formyl substituent, makes it an invaluable intermediate for constructing complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs). This compound is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its reactive halogen and aldehyde functional groups.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Peptidomimetic Scaffold Construction: The piperidine core is utilized to build constrained peptide analogs and protease inhibitors.

Basic Information

Product Name	2-Bromo-4-Formylpiperidine
CAS No.	916791-91-8
Molecular Formula	C6H10BrNO
Molecular Weight	192.06 g/mol
Synonyms	4-Formyl-2-bromopiperidine; 2-Bromo-4-piperidinecarboxaldehyde; 2-Bromo-4-piperidinealdehyde; 2-Bromo-4-formyl-piperidine; 2-Bromo-4-oxopiperidine (tautomeric form); Piperidine-4-carboxaldehyde, 2-bromo-; 916791-91-8
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Formylpiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.