Description

1-(2-Methanesulfonyl-Phenyl)-Piperazine Dihydrochloride is a high-purity, synthetically versatile piperazine derivative used as a critical building block in advanced pharmaceutical research and development. Its core value lies in providing a reliable and well-characterized intermediate for constructing complex molecules targeting central nervous system (CNS) disorders. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly those focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those with potential psychotropic or neurological activity.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Research: May be utilized in the study of specific receptor-ligand interactions and biochemical pathways.

Basic Information

Product Name	1-(2-Methanesulfonyl-Phenyl)-Piperazine Dihydrochloride
CAS No.	916488-42-1
Molecular Formula	C11H16N2O2S · 2HCl
Molecular Weight	337.25 g/mol (for dihydrochloride salt)
Synonyms	1-(2-Methanesulfonylphenyl)piperazine dihydrochloride; 1-(2-Methylsulfonylphenyl)piperazine dihydrochloride; 2-(Piperazin-1-yl)benzenesulfonylmethane dihydrochloride; 1-(2-Mesylphenyl)piperazine dihydrochloride; 916488-42-1; UNII-8V3Q8Q179N
EINECS	Contact for details

Quality Control

Our 1-(2-Methanesulfonyl-Phenyl)-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and heavy metals to ensure it meets stringent specifications for research use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.