Description

4-Amino-1-(4-Fluoro-Benzyl)-Piperidine-4-Carboxylic Acid Methyl Ester Dihydrochloride is a high-purity, pharmaceutically relevant piperidine derivative. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) in the synthesis of complex drug molecules. It is primarily utilized by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, especially within chemical libraries for high-throughput screening.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis: A starting material for the contract synthesis of specialized, non-commercial compounds for client-specific research programs.

Basic Information

Product Name	4-Amino-1-(4-Fluoro-Benzyl)-Piperidine-4-Carboxylic Acid Methyl Ester Dihydrochloride
CAS No.	916422-84-9
Molecular Formula	C15H22Cl2FN2O2
Molecular Weight	367.25 g/mol
Synonyms	4-Amino-1-[(4-fluorophenyl)methyl]piperidine-4-carboxylic acid methyl ester dihydrochloride; Methyl 4-amino-1-(4-fluorobenzyl)piperidine-4-carboxylate dihydrochloride; 1-(4-Fluorobenzyl)-4-aminopiperidine-4-carboxylic acid methyl ester hydrochloride; 4-Amino-1-(4-fluorobenzyl)piperidine-4-carboxylic acid methyl ester, 2HCl; 916422-84-9; UNII-0H6K6V8Z9C; 0H6K6V8Z9C
EINECS	Contact for details

Quality Control

Our 4-Amino-1-(4-Fluoro-Benzyl)-Piperidine-4-Carboxylic Acid Methyl Ester Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring material that meets GMP-grade standards for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.