Description

4-Allyl 1-(9-H-Fluoren-9-Ylmethyl) Hydrogen (2S)-Piperazine-1,2,4-Tricarboxylate is a high-purity, specialized chiral piperazine derivative designed for advanced chemical synthesis. This compound is a critical building block in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and oncological targets.
• Peptidomimetic Synthesis: Used to construct complex molecular scaffolds that mimic peptide structures, enhancing metabolic stability and bioavailability in drug candidates.
• Asymmetric Synthesis: Serves as a versatile chiral auxiliary or building block in stereoselective chemical reactions to create enantiomerically pure compounds.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways and developing novel synthetic methodologies.
• Ligand and Catalyst Development: Potential precursor for creating specialized ligands used in catalysis and molecular recognition studies.

Basic Information

Product Name	4-Allyl 1-(9-H-Fluoren-9-Ylmethyl) Hydrogen (2S)-Piperazine-1,2,4-Tricarboxylate
CAS No.	915707-71-0
Molecular Formula	C26H26N2O6
Molecular Weight	462.50 g/mol
Synonyms	(2S)-1-[(9H-Fluoren-9-yl)methyl] 4-(prop-2-en-1-yl) piperazine-1,2,4-tricarboxylate; 4-Allyl-1-Fmoc-piperazine-2-carboxylic acid; Fmoc-Pip(2-COOH)-Allyl; 1-Fmoc-4-allyl-piperazine-2-carboxylic acid; (S)-1-((9H-Fluoren-9-yl)methyl) 4-allyl piperazine-1,2,4-tricarboxylate; 4-Allyl-1-[(9H-fluoren-9-yl)methyl] (2S)-piperazine-1,2,4-tricarboxylate; 915707-71-0; Allyl-Fmoc-piperazine-2-COOH
EINECS	Contact for details

Quality Control

Every batch of 4-Allyl 1-(9-H-Fluoren-9-Ylmethyl) Hydrogen (2S)-Piperazine-1,2,4-Tricarboxylate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) with specifications for assay, chiral purity, and related substances is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.