Description

(S)-1-n-Boc-3-Cyanopiperidine is a high-purity chiral piperidine derivative, serving as a critical building block in modern organic synthesis. Its value lies in its dual functionality, providing both a protected amine and a versatile nitrile group for further chemical elaboration. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and other fine chemicals requiring stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, especially those targeting the central nervous system.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is required for biological activity.
• Asymmetric Synthesis: Employed as a precursor for chiral ligands, catalysts, and other auxiliaries in stereoselective transformations.
• Peptidomimetics & Bioactive Compounds: Serves as a constrained scaffold for designing peptide analogs and other bioactive molecules.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high enantiomeric purity.

Basic Information

Product Name	(S)-1-n-Boc-3-Cyanopiperidine
CAS No.	915226-39-0
Molecular Formula	C11H18N2O2
Molecular Weight	210.27 g/mol
Synonyms	1-Boc-3-cyano-(S)-piperidine; (S)-1-(tert-Butoxycarbonyl)-3-cyanopiperidine; (S)-3-Cyano-1-Boc-piperidine; (S)-1-Boc-3-cyano-piperidine; tert-Butyl (S)-3-cyanopiperidine-1-carboxylate; (3S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidine-3-carbonitrile; (S)-1-N-Boc-3-cyanopiperidine; (S)-3-Cyanopiperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (S)-1-n-Boc-3-Cyanopiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards, with typical specifications focusing on chiral purity (enantiomeric excess) and chemical purity. Certificates of Analysis (COA) detailing results for assay, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.