Description

1-[2-Fluoro-4-(Methylsulfonyl)Phenyl]Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct fluorinated and sulfonated aromatic piperidine structure. This compound is critical for medicinal chemistry research and development, offering a versatile building block for creating novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its fluorinated and piperidine motifs.
• API Synthesis: Serves as a precursor in the multi-step manufacturing of complex target molecules for clinical development.
• Biochemical Tool Compound: Potential use in developing probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	1-[2-Fluoro-4-(Methylsulfonyl)Phenyl]Piperidine-4-Carboxylic Acid
CAS No.	914637-69-7
Molecular Formula	C14H16FNO4S
Molecular Weight	313.35 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-[2-fluoro-4-(methylsulfonyl)phenyl]-; 1-(2-Fluoro-4-methanesulfonylphenyl)piperidine-4-carboxylic acid; 914637-69-7; 1-[2-Fluoro-4-(methylsulfonyl)phenyl]piperidine-4-carboxylic acid; 1-(2-Fluoro-4-(methylsulfonyl)phenyl)piperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[2-Fluoro-4-(Methylsulfonyl)Phenyl]Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.