Description

4-(4-[Bis(4-Fluorophenyl)Methyl]Piperazin-1-Yl)Phenylamine is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine and aromatic amine functional groups. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and fine chemical manufacturers seeking a reliable building block for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with CNS activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs producing specialized compounds.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and receptor studies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Item	Details
Product Name	4-(4-[Bis(4-Fluorophenyl)Methyl]Piperazin-1-Yl)Phenylamine
CAS No.	914349-65-8
Molecular Formula	C23H23F2N3
Molecular Weight	379.45 g/mol
Synonyms	1-[4-Aminophenyl]-4-[bis(4-fluorophenyl)methyl]piperazine; 4-[4-[Bis(4-fluorophenyl)methyl]-1-piperazinyl]benzenamine; 4-(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)aniline; 914349-65-8; 4-(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)phenylamine; 4-(4-(Di(4-fluorophenyl)methyl)piperazin-1-yl)aniline
EINECS	Contact for details

Quality Control

Our 4-(4-[Bis(4-Fluorophenyl)Methyl]Piperazin-1-Yl)Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.