Description

1-[Bis(4-Fluorophenyl)Methyl]-4-(4-Nitrobenzyl)Piperazine is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is valued for its complex molecular architecture, which serves as a critical building block for synthesizing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists exploring structure-activity relationships (SAR) in new chemical entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of potential active ingredients requiring a substituted piperazine core.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor binding assays due to its specific functional groups.
• Fine Chemical Production: An important building block for custom synthesis and contract manufacturing organizations (CMOs) serving the life sciences sector.

Basic Information

Product Name	1-[Bis(4-Fluorophenyl)Methyl]-4-(4-Nitrobenzyl)Piperazine
CAS No.	914349-64-7
Molecular Formula	C24H23F2N3O2
Molecular Weight	423.46 g/mol
Synonyms	4-Nitrobenzyl 1-[bis(4-fluorophenyl)methyl]piperazine; 1-[(4,4'-Difluorodiphenyl)methyl]-4-[(4-nitrophenyl)methyl]piperazine; 1-[Bis(4-fluorophenyl)methyl]-4-(4-nitrobenzyl)piperazine; 914349-64-7; 1-[(4-Fluorophenyl)(4-fluorophenyl)methyl]-4-[(4-nitrophenyl)methyl]piperazine; 4-[(4-Nitrophenyl)methyl]-1-[(4-fluorophenyl)(4-fluorophenyl)methyl]piperazine
EINECS	Contact for details

Quality Control

Our 1-[Bis(4-Fluorophenyl)Methyl]-4-(4-Nitrobenzyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP-compliant development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.