Description

2-Piperazin-1-Yl-5-Trifluoromethylbenzaldehyde is a high-value, multi-functional chemical intermediate featuring a benzaldehyde core substituted with a piperazine ring and a trifluoromethyl group. This unique structure makes it a critical building block for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and organic electronic materials due to its electron-withdrawing characteristics.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Piperazin-1-Yl-5-Trifluoromethylbenzaldehyde
CAS No.	914347-13-0
Molecular Formula	C12H13F3N2O
Molecular Weight	258.24 g/mol
Synonyms	5-(Trifluoromethyl)-2-(1-piperazinyl)benzaldehyde; 2-(Piperazin-1-yl)-5-(trifluoromethyl)benzaldehyde; 1-[4-(Trifluoromethyl)-2-formylphenyl]piperazine; 914347-13-0; Benzaldehyde, 2-(1-piperazinyl)-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Piperazin-1-Yl-5-Trifluoromethylbenzaldehyde is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.