Description

4-(4-Bromophenyl)Piperidine-4-Carboxylic Acid is a high-value, multi-functional piperidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromophenyl group and a carboxylic acid moiety, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and plant growth regulators that require specific halogenated aromatic systems.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the bromophenyl group facilitates further functionalization via cross-coupling reactions.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags to study biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(4-Bromophenyl)Piperidine-4-Carboxylic Acid
CAS No.	913542-80-0
Molecular Formula	C12H14BrNO2
Molecular Weight	284.15 g/mol
Synonyms	4-(4-Bromophenyl)-4-piperidinecarboxylic acid; 4-(p-Bromophenyl)isonipecotic acid; 4-(4-Bromophenyl)piperidine-4-carboxylic acid; 4-Carboxy-4-(4-bromophenyl)piperidine; 1,2,3,6-Tetrahydro-4-(4-bromophenyl)isonipecotic acid; 4-(4-Bromophenyl)-1,2,3,6-tetrahydropyridine-4-carboxylic acid; 913542-80-0; 4-(4-Bromophenyl)piperidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our 4-(4-Bromophenyl)Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, for comprehensive identity and purity verification. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.