Description

tert-Butyl 4-(3-Isopropyl-1,2,4-Oxadiazol-5-Yl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core modified with a 1,2,4-oxadiazole heterocycle. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting central nervous system (CNS) and metabolic disorders. It is primarily sought by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially those with piperidine-based pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for various therapeutic targets.
• API Synthesis: Serves as a building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and enzyme functions.
• Contract Manufacturing: Supplied to CDMOs for scale-up and cGMP production of clinical trial materials.
• Academic Research: Employed in university and institutional labs for novel heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	tert-Butyl 4-(3-Isopropyl-1,2,4-Oxadiazol-5-Yl)Piperidine-1-Carboxylate
CAS No.	913264-42-3
Molecular Formula	C15H25N3O3
Molecular Weight	295.38 g/mol
Synonyms	1-Boc-4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidine; tert-Butyl 4-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxylate; 4-(3-Isopropyl-[1,2,4]oxadiazol-5-yl)-piperidine-1-carboxylic acid tert-butyl ester; BOC-4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidine; 913264-42-3; 1,2,4-Oxadiazole, 5-[1-[(1,1-dimethylethoxy)carbonyl]-4-piperidinyl]-3-(1-methylethyl)-
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Isopropyl-1,2,4-Oxadiazol-5-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications from early-stage research through to pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.