Description

5-(4-Methyl-Piperazin-1-Ylmethyl)-2,3-Dihydro-1H-Isoindole is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and manufacturers of fine chemicals seeking reliable, high-quality raw materials for critical synthesis steps.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• API Synthesis: Serves as a key building block for constructing complex molecular architectures found in potential therapeutic agents.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new synthetic routes and studying structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds under cGMP conditions.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	5-(4-Methyl-Piperazin-1-Ylmethyl)-2,3-Dihydro-1H-Isoindole
CAS No.	912999-93-0
Molecular Formula	C15H21N3
Molecular Weight	243.35 g/mol
Synonyms	5-[(4-Methylpiperazin-1-yl)methyl]-2,3-dihydro-1H-isoindole; 5-((4-Methylpiperazin-1-yl)methyl)isoindoline; 2,3-Dihydro-5-[(4-methyl-1-piperazinyl)methyl]-1H-isoindole; 1H-Isoindole, 2,3-dihydro-5-[(4-methyl-1-piperazinyl)methyl]-; 912999-93-0; 5-(4-Methylpiperazin-1-ylmethyl)isoindoline
EINECS	Contact for details

Quality Control

Our 5-(4-Methyl-Piperazin-1-Ylmethyl)-2,3-Dihydro-1H-Isoindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.