Description

1-(4-Methylbenzenesulfonyl)-2-Phenylpiperazine is a specialized sulfonamide derivative of piperazine, serving as a valuable synthetic intermediate in advanced organic chemistry. Its core value lies in its structural framework, which is pivotal for constructing complex molecules with potential biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable sulfonyl and phenylpiperazine groups.
• Agrochemical Development: Serves as a precursor in the creation of new pesticides and herbicides, leveraging its heterocyclic core.
• Chemical Synthesis: Acts as a versatile reagent for introducing the N-tosylpiperazine moiety into more complex molecular architectures.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and exploratory synthesis.

Basic Information

Product Name	1-(4-Methylbenzenesulfonyl)-2-Phenylpiperazine
CAS No.	912763-17-8
Molecular Formula	C17H20N2O2S
Molecular Weight	316.42 g/mol
Synonyms	2-Phenyl-1-(p-toluenesulfonyl)piperazine; 1-(p-Tolylsulfonyl)-2-phenylpiperazine; N-(p-Toluenesulfonyl)-2-phenylpiperazine; 2-Phenyl-1-tosylpiperazine; 1-Tosyl-2-phenylpiperazine; 1-(4-Methylphenyl)sulfonyl-2-phenylpiperazine; 1-(4-Methylbenzenesulfonyl)-2-phenylpiperazine; 912763-17-8
EINECS	Contact for details

Quality Control

Our 1-(4-Methylbenzenesulfonyl)-2-Phenylpiperazine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.