Description

4-Imidazol-1-Ylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. Its primary commercial value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel drug candidates, especially within therapeutic areas requiring imidazole and piperazine pharmacophores.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) targeting various disease mechanisms.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, particularly in oncology, CNS disorders, and anti-infective research.
• Chemical Biology Probes: Serves as a precursor for creating tool compounds and probes to study biological pathways and protein function.
• Peptidomimetic Synthesis: Integral for constructing non-peptide scaffolds that mimic peptide structures, enhancing metabolic stability and bioavailability.
• Ligand Development: Used in the creation of specialized ligands for catalysis or receptor binding studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and scale-up activities.

Basic Information

Product Name	4-Imidazol-1-Ylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	912763-05-4
Molecular Formula	C14H24N4O2
Molecular Weight	280.37 g/mol
Synonyms	1-Boc-4-(1H-imidazol-1-ylmethyl)piperazine; tert-Butyl 4-((1H-imidazol-1-yl)methyl)piperazine-1-carboxylate; 4-(Imidazol-1-ylmethyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(1,1-Dimethylethyl) 4-[(1H-imidazol-1-yl)methyl]-1-piperazinecarboxylate; N-Boc-4-(imidazol-1-ylmethyl)piperazine; Piperazine, 4-[(1H-imidazol-1-yl)methyl]-, 1-(1,1-dimethylethyl) ester; 912763-05-4
EINECS	Contact for details

Quality Control

Our 4-Imidazol-1-Ylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is characterized by comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.