Description

2-Chloro-5-Thiophen-2-Yl-Pyrazine is a high-value heterocyclic building block featuring a pyrazine core substituted with both chloro and thiophene groups. This compound matters for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or conductive polymers.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Academic & Contract Research: Essential for medicinal chemistry programs and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	2-Chloro-5-Thiophen-2-Yl-Pyrazine
CAS No.	912762-30-2
Molecular Formula	C8H5ClN2S
Molecular Weight	196.66 g/mol
Synonyms	2-Chloro-5-(thiophen-2-yl)pyrazine; 2-(2-Chloropyrazin-5-yl)thiophene; 5-(2-Thienyl)-2-chloropyrazine; Pyrazine, 2-chloro-5-(2-thienyl)-; 2-Chloro-5-(2-thienyl)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Thiophen-2-Yl-Pyrazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.