Description

tert-Butyl 4-Benzyl-2-Phenylpiperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of complex, nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent pharmaceutical candidates, especially those targeting neurological receptors.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Academic Research: A valuable reagent for studying piperazine chemistry, N-Boc protection/deprotection strategies, and novel coupling reactions.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing specialized, high-value compounds for client projects.

Basic Information

Product Name	tert-Butyl 4-Benzyl-2-Phenylpiperazine-1-Carboxylate
CAS No.	911705-58-3
Molecular Formula	C22H28N2O2
Molecular Weight	352.47 g/mol
Synonyms	1-Boc-4-Benzyl-2-phenylpiperazine; tert-Butyl 4-benzyl-2-phenyl-1-piperazinecarboxylate; 4-Benzyl-2-phenylpiperazine-1-carboxylic acid tert-butyl ester; 2-Phenyl-4-benzylpiperazine-1-carboxylic acid tert-butyl ester; N-Boc-4-benzyl-2-phenylpiperazine; 1-(tert-Butoxycarbonyl)-4-benzyl-2-phenylpiperazine; BOC-4-Benzyl-2-phenylpiperazine; 911705-58-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Benzyl-2-Phenylpiperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced analytical techniques such as HPLC, GC, NMR, and mass spectrometry. We adhere to relevant industry standards to support our global clientele in their critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.