Description

tert-Butyl 3-Oxo-2-Phenylpiperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the piperazine class of heterocyclic compounds. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• API Synthesis: Used as a building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Development & Scale-up: Employed in the development and optimization of robust, scalable manufacturing processes for target molecules.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and bespoke intermediates.

Basic Information

Product Name	tert-Butyl 3-Oxo-2-Phenylpiperazine-1-Carboxylate
CAS No.	911705-40-3
Molecular Formula	C15H20N2O3
Molecular Weight	276.33 g/mol
Synonyms	1-Boc-3-oxo-2-phenylpiperazine; tert-Butyl 2-phenyl-3-oxopiperazine-1-carboxylate; 2-Phenyl-3-oxopiperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-2-phenylpiperazine-3-one; 911705-40-3; Boc-2-phenyl-3-oxopiperazine
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 3-Oxo-2-Phenylpiperazine-1-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.