Description

2-(Hydroxymethyl)-4-Thiomorpholinecarboxylic Acid 1,1-Dimethylethyl Ester is a protected thiomorpholine derivative, a key intermediate in advanced organic synthesis. This compound matters for its role as a versatile building block in the development of pharmaceuticals and bioactive molecules, offering a strategic handle for further functionalization. It is primarily needed by research and development chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the thiomorpholine scaffold.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing novel chemical libraries in drug discovery programs targeting various diseases.
• Agrochemical Synthesis: Used in the development of new crop protection agents and herbicides where the thiomorpholine moiety imparts specific biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating novel ligands used in asymmetric catalysis and metal complexation.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Peptidomimetics: Useful in the design and synthesis of peptide analogs and mimetics for biochemical research.

Basic Information

Product Name	2-(Hydroxymethyl)-4-Thiomorpholinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	911223-24-0
Molecular Formula	C10H19NO3S
Molecular Weight	233.33 g/mol
Synonyms	tert-Butyl 2-(hydroxymethyl)-1,4-thiazepane-4-carboxylate; 1,1-Dimethylethyl 2-(hydroxymethyl)-1,4-thiazepane-4-carboxylate; 2-(Hydroxymethyl)-1,4-thiazepane-4-carboxylic acid tert-butyl ester; 4-tert-Butoxycarbonyl-2-hydroxymethyl-1,4-thiazepane; Boc-2-(hydroxymethyl)thiomorpholine; tert-Butyl 2-(hydroxymethyl)thiomorpholine-4-carboxylate; 911223-24-0; BOC-Thiomorpholine-2-methanol
EINECS	Contact for details

Quality Control

Our 2-(Hydroxymethyl)-4-Thiomorpholinecarboxylic Acid 1,1-Dimethylethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and other relevant methods are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.