Description

tert-Butyl 4-(2-Hydroxyethyl)-3-oxopiperazine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a versatile and protected building block for the synthesis of complex piperazine-based molecules, enabling precise structural modifications. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key protected synthon for the synthesis of novel piperazine-containing drug candidates.
• API Development: Used in research and process chemistry for constructing the core structure of potential new active pharmaceutical ingredients.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by providing a functionalized piperazine template for further derivatization.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.
• Chemical Biology Probes: Can be utilized to create labeled or tagged molecules for studying biological pathways and target engagement.

Basic Information

Product Name	tert-Butyl 4-(2-Hydroxyethyl)-3-oxopiperazine-1-carboxylate
CAS No.	910573-06-7
Molecular Formula	C11H20N2O4
Molecular Weight	244.29 g/mol
Synonyms	1-Boc-4-(2-hydroxyethyl)-3-oxopiperazine; 1-(tert-Butoxycarbonyl)-4-(2-hydroxyethyl)-2-piperazinone; 2-Piperazinone, 4-(2-hydroxyethyl)-1-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl 4-(2-hydroxyethyl)-2-oxo-1-piperazinecarboxylate; 4-(2-Hydroxyethyl)-3-oxopiperazine-1-carboxylic acid tert-butyl ester; 1-N-Boc-4-(2-hydroxyethyl)-3-oxopiperazine; Boc-4-(2-hydroxyethyl)-3-oxopiperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Hydroxyethyl)-3-oxopiperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.