Description

2-(4-Chloro-Benzyl)-Piperazine is a versatile and high-purity chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its piperazine scaffold, which is a privileged structure for imparting biological activity, making it a critical building block for pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its structural motif for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A fundamental starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.
• Academic Research: Employed in university and institutional labs for methodological development and exploratory chemistry.

Basic Information

Product Name	2-(4-Chloro-Benzyl)-Piperazine
CAS No.	910444-99-4
Molecular Formula	C11H15ClN2
Molecular Weight	210.70 g/mol
Synonyms	1-[(4-Chlorophenyl)methyl]piperazine; 4-Chlorobenzylpiperazine; 2-(4-Chlorobenzyl)piperazine; 1-(4-Chlorobenzyl)piperazine; 4-Chlorobenzyl-piperazine; N-(4-Chlorobenzyl)piperazine; p-Chlorobenzylpiperazine; 910444-99-4
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-Benzyl)-Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.