Description

2-(3,5-Difluoro-Phenyl)-Piperazine is a high-value, fluorinated piperazine derivative, a key building block in advanced organic synthesis. Its molecular structure, featuring a difluorophenyl moiety, is engineered to enhance the metabolic stability, bioavailability, and binding affinity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients in CNS drugs, oncology treatments, and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used to develop advanced herbicides and fungicides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker for designing molecular probes and enzyme inhibitors in biochemical research.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique electronic or surface properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	2-(3,5-Difluoro-Phenyl)-Piperazine
CAS No.	910444-57-4
Molecular Formula	C10H12F2N2
Molecular Weight	198.21 g/mol
Synonyms	1-(3,5-Difluorophenyl)piperazine; 3,5-Difluorophenylpiperazine; 2-(3,5-Difluorophenyl)piperazine; Piperazine, 1-(3,5-difluorophenyl)-; 910444-57-4; 1-(3,5-Difluorophenyl)piperazine hydrochloride (salt form); 3,5-Difluoroanilinopiperazine
EINECS	Contact for details

Quality Control

Every batch of 2-(3,5-Difluoro-Phenyl)-Piperazine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency meet the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay, impurity profile, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.