Description

1-[4-Chloro-2-(Methylsulfonyl)Phenyl]-4-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperazine is a high-value, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of innovative drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Serves as a precursor in the development of advanced crop protection agents and pesticides.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and receptor-ligand interactions.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Process Chemistry Development: Employed in route scouting and optimization for scalable API manufacturing processes.
• Library Synthesis: Valuable scaffold for generating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Item	Detail
Product Name	1-[4-Chloro-2-(Methylsulfonyl)Phenyl]-4-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperazine
CAS No.	909666-49-5
Molecular Formula	C18H17ClF3N3O2S
Molecular Weight	431.86 g/mol
Synonyms	4-((6-(Trifluoromethyl)pyridin-3-yl)methyl)-1-(4-chloro-2-(methylsulfonyl)phenyl)piperazine; 1-(4-Chloro-2-methanesulfonylphenyl)-4-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine; 909666-49-5; 4-((6-(Trifluoromethyl)-3-pyridinyl)methyl)-1-(4-chloro-2-(methylsulfonyl)phenyl)piperazine; 4-[(6-Trifluoromethylpyridin-3-yl)methyl]-1-[4-chloro-2-(methylsulfonyl)phenyl]piperazine
EINECS	Contact for details

Quality Control

Our production of 1-[4-Chloro-2-(Methylsulfonyl)Phenyl]-4-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperazine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.