Description

(R)-4-tert-Butylcarbonyl-2-Methylpiperazine CAS NO 909409-91-2 is a high-purity chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in enantioselective synthesis. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry is paramount for efficacy and safety.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, including potential central nervous system (CNS) agents and receptor modulators.
• Agrochemical Research: Used in developing enantiomerically pure active ingredients for advanced pesticides and herbicides.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis projects requiring high stereochemical purity.
• Academic & R&D: Employed in university and industrial research laboratories for methodological development and novel compound libraries.
• Peptidomimetics: Used in the design and synthesis of peptide analogs and conformationally restricted scaffolds.

Basic Information

Product Name	(R)-4-tert-Butylcarbonyl-2-Methylpiperazine
CAS No.	909409-91-2
Molecular Formula	C10H20N2O
Molecular Weight	184.28 g/mol
Synonyms	(R)-1-Boc-2-Methylpiperazine; (R)-N-Boc-2-Methylpiperazine; (R)-2-Methyl-1-(tert-butoxycarbonyl)piperazine; (R)-1-(tert-Butoxycarbonyl)-2-methylpiperazine; (R)-N-tert-Butoxycarbonyl-2-methylpiperazine; (R)-4-Boc-2-Methylpiperazine; tert-Butyl (R)-2-methylpiperazine-1-carboxylate; (R)-2-Methylpiperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (R)-4-tert-Butylcarbonyl-2-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.