Description

5,6-Difluoro-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine is a high-value, fluorinated tetralin amine building block used in advanced organic synthesis. This compound matters as a critical intermediate for developing novel pharmaceuticals and agrochemicals, where its unique fluorine-substituted structure imparts desirable metabolic stability and bioavailability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine atoms for enhanced biological activity and environmental persistence.
• Ligand & Catalyst Synthesis: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the research of advanced organic electronic materials and liquid crystals.
• Chemical Biology Probe Development: Utilized to create fluorinated analogs of bioactive molecules for studying metabolic pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	5,6-Difluoro-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine
CAS No.	907973-48-2
Molecular Formula	C10H11F2N
Molecular Weight	183.20 g/mol
Synonyms	1-Amino-5,6-difluoro-1,2,3,4-tetrahydronaphthalene; 5,6-Difluoro-1,2,3,4-tetrahydro-1-naphthalenamine; 5,6-Difluoro-1-amino-1,2,3,4-tetrahydronaphthalene; 1,2,3,4-Tetrahydro-5,6-difluoronaphthalen-1-amine; 5,6-Difluoro-1-tetralinamine; 5,6-Difluoro-1,2,3,4-tetrahydro-1-naphthylamine; 907973-48-2 (CAS Name); 5,6-Difluoro-1,2,3,4-tetrahydronaphthalen-1-amine
EINECS	Contact for details

Quality Control

Our 5,6-Difluoro-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This amine compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.