Description

1-(2,6-Dichloro-Phenyl)-Piperazin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its piperazinone core and dichlorophenyl substitution. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially in neurological and psychiatric research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety for constructing potential APIs with targeted biological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial APIs.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Employed in biochemical assays to study enzyme inhibition or receptor binding interactions.

Basic Information

Product Name	1-(2,6-Dichloro-Phenyl)-Piperazin-2-One
CAS No.	907972-75-2
Molecular Formula	C10H10Cl2N2O
Molecular Weight	245.11 g/mol
Synonyms	1-(2,6-Dichlorophenyl)piperazin-2-one; 2,6-Dichloro-N-(2-oxopiperazin-1-yl)aniline; 1-(2,6-Dichlorophenyl)-2-piperazinone; 2,6-Dichlorophenylpiperazinone; Piperazin-2-one, 1-(2,6-dichlorophenyl)-; 907972-75-2; CAS 907972-75-2
EINECS	Contact for details

Quality Control

Our 1-(2,6-Dichloro-Phenyl)-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development with custom purity grades and specifications aligned with cGMP principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The material should be kept under an inert atmosphere if long-term stability is required. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.