Description

Hexahydropyrazino[2,1-C][1,4]Oxazin-4(3H)-One Hydrochloride is a high-purity, heterocyclic organic compound primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries, particularly those focused on central nervous system (CNS) and other specialty drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used in the production of Active Pharmaceutical Ingredients (APIs) for potential therapeutic applications.
• Drug Discovery & Development: Serves as a crucial scaffold in the research and development of new chemical entities (NCEs) for various disease targets.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and the commercial-scale manufacturing of advanced pharmaceutical compounds.
• Biochemical Research: Used as a reagent or precursor in biochemical studies to investigate biological pathways and mechanisms.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for use in client-specific synthesis projects.

Basic Information

Product Name	Hexahydropyrazino[2,1-C][1,4]Oxazin-4(3H)-One Hydrochloride
CAS No.	907611-38-5
Molecular Formula	C8H13N3O2·HCl
Molecular Weight	219.67 g/mol (Free base: 183.21 g/mol)
Synonyms	Hexahydropyrazino[2,1-c][1,4]oxazin-4(3H)-one hydrochloride; 3,4,6,7,8,8a-Hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-4-one hydrochloride; 1,2,3,6,7,8-Hexahydro-4H-pyrazino[2,1-c][1,4]oxazin-4-one hydrochloride; 4-Oxo-1,2,3,6,7,8-hexahydro-4H-pyrazino[2,1-c][1,4]oxazine hydrochloride; 4-Oxo-3,4,6,7,8,8a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazine hydrochloride; 907611-38-5 (CAS); Pharmaceutical Intermediate BMS-1.
EINECS	Contact for details

Quality Control

Our Hexahydropyrazino[2,1-C][1,4]Oxazin-4(3H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to ensure full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single unknown impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.