Description

tert-Butyl (3S)-3-(4-Fluorophenyl)Piperazine-1-Carboxylate is a high-purity, chiral piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate, particularly valued for constructing complex molecules with specific stereochemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where the specific stereochemistry can influence biological activity.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex piperazine-based scaffolds and exploring structure-activity relationships (SAR).
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis to create enantiomerically pure compounds.

Basic Information

Product Name	tert-Butyl (3S)-3-(4-Fluorophenyl)Piperazine-1-Carboxylate
CAS No.	906003-87-0
Molecular Formula	C15H21FN2O2
Molecular Weight	280.34 g/mol
Synonyms	1-Boc-3-(4-Fluorophenyl)-(S)-Piperazine; (S)-1-Boc-3-(4-Fluorophenyl)piperazine; (3S)-1-(tert-Butoxycarbonyl)-3-(4-fluorophenyl)piperazine; tert-Butyl (S)-3-(4-fluorophenyl)piperazine-1-carboxylate; (S)-tert-Butyl 3-(4-fluorophenyl)piperazine-1-carboxylate; 906003-87-0; 1-N-BOC-3-(4-FLUOROPHENYL)-(S)-PIPERAZINE
EINECS	Contact for details

Quality Control

Our tert-Butyl (3S)-3-(4-Fluorophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is stable under these conditions but should be kept away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.