Description

Ethyl 2-Piperazine-4-(3-Chloro)Phenyl Thiazole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. Its complex heterocyclic structure, featuring a piperazine-linked thiazole core, makes it a critical building block for the synthesis of novel bioactive molecules. This compound is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for novel APIs containing fused thiazole-piperazine pharmacophores.
• Chemical Biology & Medicinal Chemistry: Employed as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for investigating new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	Ethyl 2-Piperazine-4-(3-Chloro)Phenyl Thiazole-5-Carboxylate
CAS No.	905807-70-7
Molecular Formula	C16H18ClN3O2S
Molecular Weight	351.85 g/mol
Synonyms	Ethyl 2-(4-(3-chlorophenyl)piperazin-1-yl)thiazole-5-carboxylate; 5-Thiazolecarboxylic acid, 2-[4-(3-chlorophenyl)-1-piperazinyl]-, ethyl ester; 2-(4-(3-Chlorophenyl)piperazin-1-yl)thiazole-5-carboxylic acid ethyl ester; 905807-70-7; Ethyl 2-[4-(3-chlorophenyl)piperazin-1-yl]-1,3-thiazole-5-carboxylate; 1,3-Thiazole-5-carboxylic acid, 2-[4-(3-chlorophenyl)-1-piperazinyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Piperazine-4-(3-Chloro)Phenyl Thiazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.