Description

Ethyl 2-Piperazine-4-(4-Trifluoromethyl)Phenyl Thiazole-5-Carboxylate is a high-value, multi-functional heterocyclic compound featuring a piperazine-thiazole core and a trifluoromethylphenyl group. This molecular architecture makes it a critical advanced pharmaceutical intermediate for the development of novel active ingredients. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams requiring a sophisticated building block for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its piperazine and thiazole pharmacophores.
• Active Pharmaceutical Ingredient (API) Development: Serves as a building block in the multi-step synthesis of complex APIs, leveraging the chemical stability and bioactivity of the thiazole ring.
• Biochemical Tool Compound: Employed in academic and industrial research to probe biological pathways and enzyme interactions.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	Ethyl 2-Piperazine-4-(4-Trifluoromethyl)Phenyl Thiazole-5-Carboxylate
CAS No.	905807-67-2
Molecular Formula	C17H18F3N3O2S
Molecular Weight	385.40 g/mol
Synonyms	Ethyl 2-(piperazin-1-yl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylate; 1,3-Thiazole-5-carboxylic acid, 2-(1-piperazinyl)-4-[4-(trifluoromethyl)phenyl]-, ethyl ester; 2-Piperazin-1-yl-4-[4-(trifluoromethyl)phenyl]thiazole-5-carboxylic acid ethyl ester; 905807-67-2; Ethyl 2-(piperazin-1-yl)-4-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-Piperazine-4-(4-Trifluoromethyl)Phenyl Thiazole-5-Carboxylate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development use. All materials are characterized by modern analytical techniques, including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong alkali and fluoride sources; ensure appropriate segregation in storage areas. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.