Description

5-(4-Methyl-Piperazin-1-Yl)-2-Nitro-Benzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzaldehyde core substituted with a nitro group and a methylpiperazine moiety. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• API Synthesis: Used in the construction of complex molecules for potential use as antipsychotic, antidepressant, or anticancer agents.
• Chemical Research & Development: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Academic Research: Employed in universities and research institutes for studying organic reaction mechanisms and developing new synthetic methodologies.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific projects.

Basic Information

Product Name	5-(4-Methyl-Piperazin-1-Yl)-2-Nitro-Benzaldehyde
CAS No.	904895-82-5
Molecular Formula	C13H17N3O3
Molecular Weight	263.30 g/mol
Synonyms	2-Nitro-5-(4-methylpiperazin-1-yl)benzaldehyde; 5-(4-Methyl-1-piperazinyl)-2-nitrobenzaldehyde; Benzaldehyde, 5-(4-methyl-1-piperazinyl)-2-nitro-; 904895-82-5; 2-Nitro-5-(N-methylpiperazino)benzaldehyde; 5-(4-Methylpiperazin-1-yl)-2-nitrobenzaldehyde
EINECS	Contact for details

Quality Control

Our 5-(4-Methyl-Piperazin-1-Yl)-2-Nitro-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications are aligned with industry standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); prolonged exposure to air and light should be avoided. Keep container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.