Description

8-Oxo-5,8-Dihydro-Pyrido[2,3-B]Pyrazine-7-Carboxylic Acid Ethyl Ester is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly within kinase inhibitor and anticancer research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Anticancer Drug Research: Used in the discovery and development of novel small-molecule candidates for oncology applications.
• Chemical Biology Probes: Serves as a scaffold for creating tools to study enzyme function and cellular signaling pathways.
• Organic Synthesis: A versatile precursor for constructing complex fused pyrazine and pyridine ring systems in academic and industrial research.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	8-Oxo-5,8-Dihydro-Pyrido[2,3-B]Pyrazine-7-Carboxylic Acid Ethyl Ester
CAS No.	904818-78-6
Molecular Formula	C11H11N3O3
Molecular Weight	233.22 g/mol
Synonyms	Ethyl 8-oxo-5,8-dihydropyrido[2,3-b]pyrazine-7-carboxylate; 7-Carbethoxy-5,8-dihydro-8-oxopyrido[2,3-b]pyrazine; 8-Oxo-5,8-dihydro-pyrido[2,3-b]pyrazine-7-carboxylic acid ethyl ester; Pyrido[2,3-b]pyrazine-7-carboxylic acid, 5,8-dihydro-8-oxo-, ethyl ester; CAS 904818-78-6; Ethyl 5,8-dihydro-8-oxopyrido[2,3-b]pyrazine-7-carboxylate
EINECS	Contact for details

Quality Control

Our 8-Oxo-5,8-Dihydro-Pyrido[2,3-B]Pyrazine-7-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.