Description

1-(2-Nitro-Phenyl)-3-Phenyl-Piperazine is a specialized piperazine derivative featuring both phenyl and nitrophenyl substituents, creating a unique chemical scaffold. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection and pest management.
• Chemical Synthesis: Serves as a precursor for creating more complex heterocyclic compounds and functionalized piperazines.
• Material Science: Investigated as a monomer or additive in the development of specialty polymers and advanced materials.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological studies and discovery chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules on various scales.

Basic Information

Product Name	1-(2-Nitro-Phenyl)-3-Phenyl-Piperazine
CAS No.	904818-42-4
Molecular Formula	C16H17N3O2
Molecular Weight	283.33 g/mol
Synonyms	1-(2-Nitrophenyl)-3-phenylpiperazine; 3-Phenyl-1-(2-nitrophenyl)piperazine; 1-(2-Nitrophenyl)-3-phenyl-1,4-diazepane; 904818-42-4; 1-(2-Nitro-Phenyl)-3-Phenyl-Piperazine; 2-Nitrophenyl-3-phenylpiperazine; N-(2-Nitrophenyl)-N'-(phenyl)piperazine
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for 1-(2-Nitro-Phenyl)-3-Phenyl-Piperazine typically meets a purity specification of ≥95% (by HPLC), with comprehensive identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents. We support custom synthesis and can tailor purity grades (including >98% and >99%) to meet specific project requirements under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to direct light should be avoided. Keep the container tightly sealed to minimize contact with moisture and air.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.