Description

4-(5-Carboxy-Pyridin-2-Yl)-2-Methyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-value, multi-functional chemical building block featuring both a protected carboxylic acid and a piperazine ring system. This compound is critical for pharmaceutical research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of proprietary APIs, leveraging its piperazine and pyridine motifs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where its heterocyclic structure contributes to biological efficacy.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes and tools for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	4-(5-Carboxy-Pyridin-2-Yl)-2-Methyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	904817-70-5
Molecular Formula	C17H23N3O4
Molecular Weight	333.38 g/mol
Synonyms	2-Methyl-4-(5-carboxypyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(5-carboxypyridin-2-yl)-2-methylpiperazine-1-carboxylate; 4-(5-Carboxy-2-pyridyl)-2-methylpiperazine-1-carboxylic acid tert-butyl ester; 904817-70-5; 2-Pyridinecarboxylic acid, 6-[4-[(1,1-dimethylethoxy)carbonyl]-3-methyl-1-piperazinyl]-; 6-[4-(tert-Butoxycarbonyl)-3-methylpiperazin-1-yl]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(5-Carboxy-Pyridin-2-Yl)-2-Methyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.