Description

4-[2-Hydroxyimino-2-(4-Methoxy-Phenyl)-Ethyl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperazine and oxime functional groups. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and R&D organizations focused on developing new therapeutic agents, especially within the central nervous system and oncology drug pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Process Chemistry Development: Used in route scouting and optimization for scalable, GMP-compliant manufacturing processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical development programs.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	4-[2-Hydroxyimino-2-(4-Methoxy-Phenyl)-Ethyl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	904815-72-1
Molecular Formula	C18H27N3O4
Molecular Weight	349.43 g/mol
Synonyms	tert-Butyl 4-[2-(hydroxyimino)-2-(4-methoxyphenyl)ethyl]piperazine-1-carboxylate; 1-Boc-4-[2-(hydroxyimino)-2-(4-methoxyphenyl)ethyl]piperazine; 4-[2-Hydroxyimino-2-(4-Methoxy-Phenyl)-Ethyl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester; 904815-72-1; 1-(1,1-Dimethylethyl) 4-[2-(hydroxyimino)-2-(4-methoxyphenyl)ethyl]-1-piperazinecarboxylate; Boc-Piperazine Oxime Derivative; (4-Methoxyphenyl)(piperazin-1-yl)methanone oxime tert-Butyl carbamate derivative
EINECS	Contact for details

Quality Control

Our 4-[2-Hydroxyimino-2-(4-Methoxy-Phenyl)-Ethyl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.