Description

4-(2-Carboxy-6-Nitro-Phenyl)-Piperazine-1-Carboxylic Acid Tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine and nitro-substituted aromatic structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, especially in medicinal chemistry research and development.
• API Synthesis: Serves as a key building block for constructing active pharmaceutical ingredients (APIs) with piperazine-based pharmacophores.
• CNS Drug Development: Used in the research and production of potential therapeutics for central nervous system disorders.
• Chemical Research: Employed in academic and industrial laboratories for method development and the exploration of new chemical entities.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	4-(2-Carboxy-6-Nitro-Phenyl)-Piperazine-1-Carboxylic Acid Tert-Butyl Ester
CAS No.	904814-87-5
Molecular Formula	C16H21N3O6
Molecular Weight	351.36 g/mol
Synonyms	4-(2-Carboxy-6-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(2-carboxy-6-nitrophenyl)piperazine; tert-Butyl 4-(2-carboxy-6-nitrophenyl)piperazine-1-carboxylate; 904814-87-5; 4-(2-Carboxy-6-Nitro-Phenyl)-Piperazine-1-Carboxylic Acid Tertier-Butyl Ester; 1-(tert-Butoxycarbonyl)-4-(2-carboxy-6-nitrophenyl)piperazine; Boc-4-(2-COOH-6-NO2-Ph)-piperazine
EINECS	Contact for details

Quality Control

Our 4-(2-Carboxy-6-Nitro-Phenyl)-Piperazine-1-Carboxylic Acid Tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.