Description

3-Phenyl-Piperazine-1-Carboxylic Acid Ethyl Ester is a high-purity, versatile piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in central nervous system (CNS) and psychiatric therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its piperazine core for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Ligand and Catalyst Preparation: Can be utilized to develop novel ligands for catalytic systems or metal complexes in asymmetric synthesis.

Basic Information

Product Name	3-Phenyl-Piperazine-1-Carboxylic Acid Ethyl Ester
CAS No.	904814-49-9
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	Ethyl 3-phenylpiperazine-1-carboxylate; 1-Carbethoxy-3-phenylpiperazine; 3-Phenylpiperazine-1-carboxylic acid ethyl ester; 1-(Ethoxycarbonyl)-3-phenylpiperazine; 904814-49-9; UNII-9V8P23M8QJ
EINECS	Contact for details

Quality Control

Our 3-Phenyl-Piperazine-1-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.