Description

3-(4-Dimethylamino-Phenyl)-Piperazine-1-Carboxylic Acid Tert-Butyl Ester is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with pharmacological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new active ingredients. The Boc-protected amine and dimethylaniline moiety make it a key precursor for drug discovery programs targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the development of new crop protection agents and pesticides, leveraging its complex heterocyclic structure.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for catalysis or as a precursor for metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, complex fine chemicals and specialty materials.

Basic Information

Product Name	3-(4-Dimethylamino-Phenyl)-Piperazine-1-Carboxylic Acid Tert-Butyl Ester
CAS No.	904814-43-3
Molecular Formula	C17H27N3O2
Molecular Weight	305.42 g/mol
Synonyms	tert-Butyl 3-[4-(dimethylamino)phenyl]piperazine-1-carboxylate; 1-Boc-3-(4-N,N-Dimethylaminophenyl)piperazine; 3-(4-(Dimethylamino)phenyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(4-dimethylaminophenyl)piperazine; 904814-43-3; 3-(4-Dimethylaminophenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 3-(4-Dimethylamino-Phenyl)-Piperazine-1-Carboxylic Acid Tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound. Store away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH limits
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.