Description

3-Bromo-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant commercial interest. Its core value lies in its unique fused triazolopyrazine structure, which is critical for the synthesis of novel bioactive compounds targeting central nervous system (CNS) disorders. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and biotechnology sectors, where it serves as a key precursor for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric conditions.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the development of potential APIs for clinical trials.
• Biochemical Tool Compound: Utilized in pharmacological research to study specific receptor interactions and enzyme inhibition.
• Process Chemistry & Scale-Up: Employed in the development of robust, scalable synthetic routes for GMP manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Product Name	3-Bromo-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride
CAS No.	903130-08-5
Molecular Formula	C6H9BrClN5
Molecular Weight	266.53 g/mol
Synonyms	3-Bromo-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine HCl; 3-Bromo-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine hydrochloride; 903130-08-5; 3-Bromo-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine hydrochloride; 3-Bromo-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.