Description

4-(2-Trifluoromethoxy-Phenoxy)-Piperidine is a high-value, fluorinated piperidine derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring a trifluoromethoxy-phenoxy moiety, makes it an essential building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily targeted at research and development (R&D) scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate sophisticated fluorinated motifs into their molecular designs.

Application

• Pharmaceutical Intermediate: Key synthon for the research and synthesis of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Active Ingredient Precursor: Used in the development of next-generation herbicides and insecticides, leveraging the stability and bioavailability imparted by the trifluoromethoxy group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for enhanced performance characteristics.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Item	Details
Product Name	4-(2-Trifluoromethoxy-Phenoxy)-Piperidine
CAS No.	902836-49-1
Molecular Formula	C12H14F3NO2
Molecular Weight	261.24 g/mol
Synonyms	4-(2-(Trifluoromethoxy)phenoxy)piperidine; 1-(2-(Trifluoromethoxy)phenoxy)-4-piperidine; 4-Piperidinol, 1-[2-(trifluoromethoxy)phenoxy]-; 902836-49-1; 4-(2-Trifluoromethoxy-phenoxy)piperidine; 4-(α,α,α-Trifluoro-o-methylphenoxy)piperidine
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Trifluoromethoxy-Phenoxy)-Piperidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.